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Toll-like receptors (TLRs) play a key role in the innate response by recognizing and binding bacterial components, including endotoxins like lipopolysaccharide (LPS), which act as immune enhancers (Bessler et al. 1990).
Protein interaction modules, such as PDZ, SH3, WW, EH, SH2 and other domains, mediate protein-protein interactions by recognizing and binding short and usually linear peptide epitopes within their interacting partners [1] [4].
Msh heterodimers initiate DNA MMR by recognizing and binding to unpaired and impaired bases.
They mediate protein-protein interactions by recognizing and binding short motifs in their ligands.
The TFs form input signals by recognizing and binding in a sequence-specific manner in the enhancer DNA at transcription factor binding sites (TFBS).
(i) Proteins that regulate cellular metabolism by recognizing and binding specific sequences of DNA typically display specificity of multiple orders of magnitude for their targets.
Similar(43)
The TAD then moves to the nucleus, where it activates transcription of target genes by recognizing and directly binding the ER stress element (ERSE) in cooperation with the transcription factor NF-Y, which is also bound to the ERSE (Yoshida et al., 1998; Yoshida et al., 2000).
In animals, they target mRNAs by recognizing and directly binding to multiple partially complementary sites preferentially located in the 3' untranslated regions (UTRs) of transcripts.
For another example, osa-miR446 regulated LOC_OS06g24594.2, LOC_OS06g24594.5 and LOC_OS06g24594.6 by recognizing the binding sites within the 2nd introns of these transcripts.
NF-κB binds as a homo- or heterodimer of Rel homology domain-containing proteins to κBREs by specifically recognizing two binding footprints surrounding a central spacer in which the AATTY site is found.
Our results indicate that TUT7 distinguishes pre-miRNA substrates at the binding step by recognizing the cis-acting elements.
More suggestions(15)
by recognizing and remembering
by recognizing and surveying
by looping and binding
by recognizing and taking
by recognizing and starting
by doublecortin and binding
by hidden and binding
by recognizing and preventing
by recognizing and concentrating
by recognizing and paying
by recognizing and exploiting
by recognizing and mastering
by recognizing and killing
by recognizing and protecting
by recognizing and upholding
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