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This association has been supported by recent studies reporting that sleep impairment is not only one of the most common symptoms of migraine but is also the most common trigger [30, 31].
This position is supported by recent studies reporting activity increases of the most inferior region of the medPFC during perspective taking of similar others [59], while dissimilar and unknown others rather activated the dorsal and most posterior region of the medPFC [12], [27].
This idea is supported by recent studies reporting up-regulation of APP in several cancers due to its growth-promoting function [ 65- 68].
This hypothesis may also be supported by recent studies reporting an association between increased T2D genetic susceptibility and reduced prostate cancer risk [ 25, 26].
Despite these limitations, the role of surveillance that is not limited to isolates causing invasive disease is shown by recent studies reporting high case-fatality rates for noninvasive serotypes (15 – 15 ).
Nevertheless, interest in the role of autoimmunity in the pathophysiology of both IPF and COPD was revived by recent studies reporting highly activated and proliferative CD4+ cells [ 11] and global numerical and functional impairment of T regulatory cells [ 12], as well as presence of circulating auto-antibodies against nuclear and cytoplasmic antigens in both IPF and COPD patients [ 13, 14].
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These findings were supported by recent studies reported by Chang's group [ 21].
This is also supported by two recent studies reporting reduced intravenous opioid requirements after intrathecal morphine (150 200 μg), with a consequent decrease in the incidence of nausea and vomiting [ 55, 56].
Interestingly, there is interaction between Treg cells and TAMs in the TME of epithelial ovarian cancer, as is evidenced by a recent study reporting that IL-10 released by TAMs enhances the frequency of Treg cells via activation of Foxp3 during T-cell differentiation and accelerates disease progression (Zhu et al., 2016).
This pressing clinical need is further underscored by a recent study reporting the burden of cCH to patients and society: more than 50%% of cCH patients reported suffering symptoms of depression; 25 % were found to have suicidal tendencies; and about 25%% received some form of disability allowance [21].
This view is supported by a recent study reporting direct intrahippocampal ERP measurements in 16 epilepsy patients during a passive oddball paradigm.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com