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These SNPs provide independent confirmation of some of the SNPs identified by custom HTS and are annotated as confirmation by "Realignment of Celera raw reads" in Table 2.
Activation upon binding to other macromolecules can be allowed by realignment of active-site residues, if they were misaligned in the unbound state, or removal of steric occlusion by a conformational transition induced upon activator binding.
confirmed by both Illumina and Applied Biosystems sequencing pipelines, confirmed by transcriptome sequencing (see Methods), confirmed by PCR directed sequencing [ 6], confirmed by realignment of Celera raw reads (see SNP Databases in Methods), or supported by imputed SNPs [ 24].
The majority of these deletion mutations are double base deletion mutations, suggesting that these double base deletion mutations arose after hRev1 incorporated two dC nucleotides into the primer strand, followed by realignment of the primer strand to loop out the +1 and +2 template positions, and subsequent extension by hPolκ.
Other researchers have suggested that the primary goal of treating 4-level CSM with ACDF should be decompression of the spinal cord, followed by realignment of the cervical spine, stabilization of the cervical spine, and correction of a cervical spinal deformity [ 10].
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The images were motion corrected by realignment to the middle volume of the 4D dataset, smoothed using a 6-mm full-width at half maximum smoothing kernel, and non-linearly registered via the participant's T1-weighted structural image to the MNI-152 template.
The dramatic opening of the external face of the DBD as the transporter moved from the partially opened outward to the fully opened outward conformation of the catalytic transition state observed here is hypothesized to occur by a realignment of coupling helices 2 and 4 caused by movements of the nucleotide binding domains during this catalytic transition.
This will be followed by a realignment of politics along not a left-right divide, but what she calls a "nationalist" and "internationalist" one.
In the closed conformation, MscS shows a more compact TM domain than in the crystal structure, characterized by a realignment of the TM segments towards the normal of the membrane.
The first such realignment occurred in the 1940s in Wayne County and was completed by the realignment of NY 104 onto the Irondequoit Wayne County Expressway near Webster in the 1980s.
At the opposite end, at Ysgwrfa, the final five locks before Glynneath have been severed by a realignment of the road and the construction of a culvert, but the road has carried a lot less traffic since the A465 bypass was opened, and could possibly be rerouted along its original course, where the bridge over the canal still exists.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com