Sentence examples for by randomizing the gene from inspiring English sources

The expected ratio of internal to total pathway edges (E IN / E T ) for each of the 128 pathways was determined by randomizing the gene lists while maintaining the Pathway Maps for each gene.

p (j, k, t, n ) = 1 − ∑ c = 0 k − 1 (j c ) (n − j t − c ) (n t ) Further, exhaustive permutations by randomizing the gene ranks was done for each GO category, followed by an interpretation of an empirical p-value from the distribution of 10,000 permutation cycles.

In order to evaluate the significance of the calculated TCS scores, permutation analysis was implemented by randomizing the orders of gene expression data (G in Eq. 2).

We estimated the false positive rate by randomizing the order of each gene vector in the discretized gene-sample matrix, then constructing the matrices – this gives around 5% of the edges found with un-shuffled data.

These Mocks were then permuted by randomizing the microarray names on a gene by gene basis (240,000 possible permuted mock arrays).

The plotted horizontal "null" relationship was obtained by randomizing the SC location of each gene before motif-preference estimation, which leaves GC content unchanged but randomizes each gene's motif preferences, resulting in identical, zero-valued GC pressures in each of the thirteen groups.

We confirmed that the null expectation of the whole-genome across-codon preference for each motif is 0.00 by randomizing the placement of SCs in each gene in the human dataset before estimating each gene's motif preferences and then using these randomized preferences to estimate a new set of average preferences.

Furthermore, a gene library based on the sbAvd-1 gene was created by randomizing the loop area between β-strands 3 and 4. Phage display selection from this library led to the isolation of a steroid-binding protein with significantly decreased biotin binding affinity compared to sbAvd-1.

To evaluate the statistical significance of candidate SNPs, we performed permutation analysis by randomly selecting HapMap SNPs (Gibbs et al., 2003) within promoter regions of human protein coding genes, and by randomizing the ranking of the transcription factors with respect to phenotypes (Section 2).

In order to minimize bias, the eQTL procedure was repeated after randomizing the gene-SNP pairs.

They evade Brightmail filters by randomizing the characteristics that filters look for.