Sentence examples for by random mutation and from inspiring English sources
It remains speculative how the genomic changes arise at the corresponding environmental response gene loci, simply by random mutation and sexual recombination, or by another internal spontaneous mutator?
BIOLOGICAL evolution happens by random mutation and selection.
These findings show how complex functions can originate by random mutation and natural selection.
Deregulation of allosteric inhibition of enzymes is a challenge for strain engineering and has been achieved so far primarily by random mutation and trial-and-error.
Microorganisms capable of efficient production of amino acids have traditionally been developed by random mutation and selection method, which might cause unwanted physiological changes in cellular metabolism.
New gene variants (i.e., alleles) are produced by random mutation, and over the course of many generations, natural selection may favor advantageous variants, causing them to become more common in the population.
The present study focused on time-series changes, but not on data variations caused largely by random mutations and sequencing uncertainty, and therefore, average characteristics of strains isolated in a similar period were analyzed, summing up the sequences isolated in one month and calculating an averaged mononucleotide composition for each month (Fig. 1b).
These short motifs arise by evolutionary convergence, i.e. by random mutations and functional selection, rather than duplication and subsequent divergent spread in the genome, such as in the case of binding domains [59].
Therefore, quantitative differences appear to be due to subtle phenotypic and genotypic changes in the complex physiology of the mouse strains, which have been separated by inbreeding for many generations (compare Ref. 12 and the literature cited therein for divergence by random mutations and various phenotypic differences documented for congenic strains).
