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Such patterns are consistent with large-scale duplication followed by random loss of either paralogous copy.
Simulation results suggest that colony social structure is robust to fragmentation caused by random loss of small numbers of roosts.
Tandem duplication followed by random loss of redundant genes has been demonstrated to be the main mechanism for gene rearrangement of adjacent tRNAs in vertebrate mt genomes [ 5].
4) "However, the lack of young families in genome is less informative because it may be caused by random loss of active source genes in founder populations".
Owing to their small numbers, hub nodes are not likely to be affected by random removal (perhaps corresponding to a mutational loss in a biological network) and thus the topology of the network is relatively unchanged by random loss of nodes.
The most commonly documented mechanism of mt genome rearrangement tandem duplication followed by random loss of genes (Boore 2000) —cannot explain gene inversion, and it has been suggested that octocoral mitochondrial genomes have evolved instead through a process involving intramolecular recombination (Brugler and France 2008; Uda et al. 2011).
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Their favored mechanism involves tandem duplication by slipped-strand mispairing followed by a random loss of genes and inversion by intramitochondrial recombination.
The process of tandem duplication followed by random loss discussed above is typical of the TDRL model.
Interestingly, this result indicates that lipid accumulation is more likely provoked by the random loss of protein phosphatase function as opposed to the random loss of function among proteins involved in lipid metabolism.
Conservation of gene copies preserving classical features accompanied by seemingly random loss of older non-classical gene duplicates is somewhat reminiscent of MHC class I evolution described for higher vertebrates [ 45].
Thus, we did a simple experiment in order to know the ratio of retransmissions caused by random loss and spurious RTOs to that of retransmissions by triggering the fast retransmission algorithm.
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by random amplification of
by random ligation of
by random drift of
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