Sentence examples for by random introduction of from inspiring English sources

This is somewhat contrary to expectations, as there is a slight difference in the chemical environment of Te1 and Te2 which gives Bi-Te1 bond a minor ionic component, favoring that Se would first preferentially replace Te2 sites [39], immediately followed by random introduction of Se at Te1 sites.

Mader et al. (2013) reported a factor of three to 4-fold lower specific productivity of 2F5scFv-Fc-producing subclones compared with 3D6scFv-Fc cell clones established by random introduction of conventional plasmid expression vectors or alternatively by bacterial artificial chromosomes (BAC) harboring the same expression elements.

We then simulated artificial selection experiments with our standard experimental parameters (N = 1000, 20%% selected, 20 generations) and canonical trait architectures, followed by the random introduction of errors based on the empirical error distributions.

Effect of mismatched oligonucleotides on HCV RNA levels was also studied by using S-ODN1 altered sequence after random introduction of a single nucleotide substitution which subsequently showed no effect on the potency of S-ODN1 to inhibit HCV replication, therefore, suggesting that S-ODN1 retains its high efficiency even after single base substitution.

These errors arise mainly from imbalances in template representation and from random introduction of point mutations caused by copying errors.

The study revealed many off-target effects (random introduction of mutations) and low efficiency levels for introduction of the corrective gene they were using.

However, we prefer to remain in the spirit of random effects modelling where we assume that covariance structures are coped with by the introduction of random effects.

This signals that more triangles have formed, a direct effect of the new connections produced by the introduction of random topics in hub nodes.

Experimentally, directed evolution relies upon iterative rounds of creation of novel protein variants by introduction of random mutations into the target gene and selection of individuals with desirable characteristics.

The disappearance of the vtc1-1 mutatinn in svt2 may also be explained by the introduction of a random mutation.

The variance about β0 has been further apportioned by the introduction of a random intercept for each visit, b0 ij, and each subject, b0 i.