Sentence examples for by random integration of from inspiring English sources

HGn39D was generated by random integration of an enhancer-trap transgene [28].

Secondly, Cre transgenic mouse strains are mostly generated by random integration of a DNA construct comprising promoter and Cre cDNA into the host DNA.

Transgenesis by random integration of naked DNA has proven much more efficient for gene supplementation, whether using PNI or SCNT.

Transgenic fly lines were obtained by random integration of the UAS-Myc-ets21c LONG transposon (Genetic Services).

The Tg[gSAGFF202A] line was generated by random integration of a gene-trap construct (Asakawa et al., 2008).

The ET krt4 EGFP sqgw57A line was generated by random integration of an gene-trap construct (Kondrychyn et al., 2011).

In addition to significantly shortening the production timeline, this strategy also enhances RP accumulation level by eliminating the "position effect" of variable expression caused by the random integration of transgene within the genome [ 4].

The establishment of high producer is an important issue in Chinese hamster ovary (CHO) cell culture considering increased heterogeneity by the random integration of a transfected foreign gene and the altered position of the integrated gene.

The TCGO mouse line was produced by the random integration of a reporter cassette in the mouse genome (reported in a manuscript currently being revised).

Furthermore, when R4 attB and attP sites are placed into the human genome, either by random integration or at a specific sequence by using the φC31 integrase, they act as targets for integration of incoming plasmids bearing R4 att sites.

Genomic targets enabling FLP RMCE can either be established by random integration (electroporation and transfection; Turan et al. 2013) or using the scout functions and integration preferences of retroviral vectors (Kuehle et al. 2014).