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Chronic airway diseases are commonly accompanied by raised expression of gel-forming mucins.
Overexpression of Akt3 by transfection of Akt3-3.1, as evidenced by raised expression of Akt3 mRNA and protein, resulted in no apparent change in cell cycle.
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Various classes of polyphenols have been shown to post-transcriptionally regulate levels of mRNA containing AU-rich elements by raising expression of RNA binding proteins [ 46– 46].
This change in phenotype is characterized by a raised expression of type I collagen and a decrease in type II collagen expression.
Our results show that most (eight out of nine) synovial sarcomas clustered as a single group based on their gene expression portrait and that this cluster was characterised by the raised expression of a set of 48 genes.
More importantly, there is good evidence that local production of BAFF contributes to deleterious effects of activated B cells by raising their expression of CD19 molecules [ 4], and ensuring survival of B-cell aggregates, and auto-antibody isotype switching outside and inside GCs [ 41].
Other oxidants (such as H2O2) have already been shown to increase APP cleavage by raising the expression of BACE-1 and, as a consequence, to enhance the production of both Aβ42 and Aβ40 (Coma et al, 2008; Shen et al, 2008; Tamagno et al, 2002; O'Connor et al, 2008).
An increase in amylose content can be accomplished by inhibiting enzymes involved in amylopectin synthesis [ 41, 42], by raising the expression levels of GBSSI [ 43], or simultaneously by raising the expression levels of AGP as well as GBSS and suppressing the expression levels of SBE [ 18].
Specifically, PAR2 activation and lipopolysaccharide (LPS) activation of TLR4 synergistically enhance inflammatory signalling in airway epithelial cells by raising the level of PAR expression and secretion of interleukin (IL -8.
The relative expression is determined by raising 2 to the power of the negative value of ∆∆Ct for each sample.
Relative expression was calculated by raising 2 to the power of the difference in Ct values.
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