Regarding ZAZG, Kumar et al. [35] detected this protein, by proteomic analysis, in urine of patients with different renal diseases, such as nephrotic syndrome, kidney failure and microalbuminuria.
Among these proteins, tubulin, actin, annexins, enolase, GAPDH, gamma-glutamyltransferase, and HSP 27 have been demonstrated to be derived from lipid raft by proteomic analysis in previous studies [40], [41], [42], [43], [44].
Also, we are working on additional potential targets recovered by proteomic analysis in our future study on this project.
Unfortunately, they found that, of around 2000 proteins identified by proteomic analysis in two metazoans, two amoebozoa, one alveolate, very few are overlapping.
These results indicate that the expression levels of proteins identified by proteomic analysis in MCF-7-MEK5 and MCF-7-VEC cells are consistent with corresponding gene expression levels.
A total of 9 Wolbachia proteins were identified by proteomic analysis in a specific tissue that was not confirmed by any transcriptomic evidence in that same tissue (Additional file 16: Figure S6A-C).
GO terms identified by transcriptomic analysis are highlighted in red while GO terms identified by proteomic analysis are in blue.
Thus, differentially regulated proteins by proteomic analysis were expressed in C. pneumoniae-infected human atheromatous heart tissue specimens and were detectable morphologically within lesions by IHC.
Several proteins involved in innate immunity (lactotransferrin, heat shock 70 kDa protein, lysosyme, neutrophil gelatinase associated lipocalin, protein S100-A8, protein S100-andand leukotriene A-4 hydrolase were identified by using proteomic analysis in the secretions of neutrophils stimulated by CHR and CAT (Figure 8C).
In addition, a small hsp, Hsp21.4 identified by proteomic analysis, is more abundant in the brain of H. armigera pupae at diapause initiation [ 11].
Collecting pure saliva from sand flies is technically challenging, so we used salivary gland lysates, which have been shown by proteomic analysis to be enriched in salivary proteins [65], as source of glycoproteins for lectin-blot analysis.
