Sentence examples for by proteolytic processing of from inspiring English sources
Following budding, HIV maturation is initiated by proteolytic processing of Gag, which induces conformational changes in the CA domain and results in the assembly of the distinctive conical capsid.
HBeAg is produced by proteolytic processing of the pre-core protein.
Picornaviral proteins are generated by proteolytic processing of a single viral polyprotein which is translated from a single ORF.
Interestingly, certain KLKs may exert antiangiogenic functions, since they have been shown to release angiostatin-like peptides by proteolytic processing of plasminogen [81].
In humans, the major cathelicidin peptide is LL-37, which is produced by proteolytic processing of its precursor hCAP18 (human cationic antimicrobial protein 18).
Mature human HCF-1 is a heterodimeric complex of stably associated amino- (HCF-1N) and carboxy- (HCF-1C) terminal subunits that are generated by proteolytic processing of a 2035-amino-acid 2035-amino-acid 2035-amino-acid
In AD, as well as the majority of mammalian AD models, Aβ must be generated by amyloidogenic proteolytic processing of APP, a process that reportedly occurs at both plasma membrane (Armstrong, 1998; Takahashi et al., 2002b; Marchesi, 2005) as well as intracellular AEL vesicles (Cataldo et al., 2004; Yu et al., 2005).
Their activation by proteolytic processing is the point-of-no-return in the commitment to apoptosis.
According to the "amyloid hypothesis," missense mutations in the APP gene promote generation of A β by favoring proteolytic processing of APP by β- or γ-secretase [ 9].
AD is a devastating neurodegenerative disorder of the brain characterized by accumulation and deposition of amyloid β (Aβ) peptide, which are generated by sequential proteolytic processing of transmembrane amyloid precursor protein (APP) by two enzymes, β-secretase (β-site APP cleaving enzyme or BACE-1) and γ-secretase, in the amyloidogenic processing pathways [ 4, 5].
An endoplasmic reticulum stress response in Arabidopsis is mediated by proteolytic processing and nuclear relocation of a membrane-associated transcription factor, bZIP28.
