Sentence examples for by proteolytic conversion of from inspiring English sources

In the case of VEGF-D, the affinity for VEGFR-2 is increased approximately 290-fold by proteolytic conversion of the full-length to the mature form (Stacker et al, 1999).

The TF/FVIIa complex may further activate FX (FXa), which together with its cofactor FVa, generates thrombin (FIIa) from prothrombin by proteolytic conversion.

Our model predicts that HSPGs increase the proteolytic conversion of matrix-binding VEGF isoforms by increasing the residence time of a VEGF molecule in a tissue's proteolytic environment.

The proteolytic conversion of prothrombin to thrombin is catalyzed by the prothrombinase complex composed of the enzyme, factor Xa, and the cofactor, factor Va, assembled on a membrane surface in the presence of Ca2+.

A major in vivo function of ECE-1 is the proteolytic conversion of big endothelin-1 to endothelin-1, one of the most potent vasconstricting peptides known.

Such increase was associated with an enhancement of tumor-secreted urokinase-type plasminogen activator, suggesting the proteolytic conversion of plasminogen to angiostatin in vitro.

It plays a critical role during the proteolytic conversion of Notch required to activate the pathway (Pan and Rubin 1997; Sotillos et al. 1997).

C3 is the most abundant complement component in plasma, occurring at about 1.0 mg/ml, and its proteolytic conversion to active C3b by the removal of its ANA domain is the central event in complement activation.

In fact, proteolytic conversion to the oxidase form was only observed after induction of pancreatitis (figure 1).

Angiotensin-converting enzyme plays a major role in the renin-angiotensin-aldosterone system, through two proteolytic mechanisms: conversion of angiotensin I to angiotensin II and degradation of bradykinin.

Gibbs, D. J. et al. Nitric oxide sensing in plants is mediated by proteolytic control of group VII ERF transcription factors.