Sentence examples for by protein expression variability from inspiring English sources

This bimodality in the NF model is due to the wide range of ERK activation thresholds introduced by protein expression variability, combined with variability in EGF-induced RasGTP levels.

We therefore explicitly included protein expression variability in the models.

Tissue homeostasis may in fact require protein expression variability.

To eliminate potential bias caused by protein expression changes, all the ratios of quantifiable Kbz and Kac peptides were normalized by corresponding histone protein expression levels.

Here, recombinant DNA-binding proteins represent signals, and recombinant genes perform the computation by regulating protein expression.

Because both proteins were expressed properly, the observed differences between the two proteins were most likely not caused by defective protein expression.

Model analysis suggests that a conversion of graded input output responses in single cells to digital responses at the population level is caused by a broad distribution of ERK pathway activation thresholds brought about by cell-to-cell variability in protein expression.

As such, the true variability in protein expression tends to be overestimated by our methods, resulting in copy number estimates that are biased low.

It is based on the constitutive expression of green fluorescent protein (GFP) mediated by the bacterial protein expression vector pGFPuv (Clontech, Palo Alto, USA).

All the Kbz site ratios were normalized by the quantified protein expression levels.

Protein expression heterogeneity by IHC, usually referred as variability in immunohistochemical intensity and extension of HER2-positive areas, is also a problem which could greatly impact on sample selection for HER2 testing in GC.