Sentence examples for by promoting the interaction from inspiring English sources

In our previous study, we demonstrated that HSCARG interacts with IKK β and suppresses its phosphorylation by promoting the interaction between PP2A and IKK β, which provided one of the possible mechanisms to explain how HSCARG inhibits IKK β phosphorylation and NF- κB activity.

Third, the serine/threonine phosphorylation of P450c17 itself promotes 17,20 lyase activity, again apparently by promoting the interaction of P450c17 with POR.

This inactivation of GSK3β enhances the anti-inflammatory pathway by promoting the interaction of phospho-CREB with CBP and, occurs in concert with an overall decrease of phospho-p65 (Ser 276) and elevated levels of the anti-inflammatory cytokine IL-10[16] IL-10[16]8], [17], [18].

For example, ASPP2 was shown to stimulate TAZ dephosphorylation, partly by promoting the interaction between TAZ and PP1; this function of ASPP2 requires the TAZ WW domain.

It was found that MALAT1 acts as a molecular scaffold to allow gene expression by promoting the interaction among unmethylated PRC2, E2F1 transcription factor, histone markers, and the other transcriptional co-activator complexes [ 54].

RSV (resveratrol) is a naturally occurring polyphenol that has been found to exert antioxidant, anti-inflammatory and neuroprotective properties, and inhibits mTOR signalling by promoting the interaction between mTOR and DEPTOR in C2C12 fibroblasts [ 10].

Previously, we reported a tumour suppressive action of KSR1 in breast cancer by stabilising BRCA1 through a reduction of its ubiquitination and by promoting the BRCA1-BARD1 interaction.

As noted above, glucose stimulates dephosphorylation of Snf1 either by direct activation of Reg1/ Glc7 or by promoting the productive interaction of Snf1 with Reg1/ Glc7.

By promoting the noncovalent interaction of nuclear proteins with PAR, PARylated PARP-1 may act as a shuttle to deliver nuclear protein PAR complexes into the CBs.

Surfactants are also known to play a role in the lung immune defence with particles deposited within the lung being pulled towards the alveoli wall by the surfactant promoting the interaction of pathogens and surfactant proteins (Schurch et al., 1992).

Second, cytochrome b5 strongly promotes 17,20 lyase activity, principally by acting as an allosteric factor promoting the interaction of P450c17 with POR, although a minor role as an alternative electron-transfer protein has not been wholly excluded.