Sentence examples for by promoting the binding from inspiring English sources

Together, these data indicate that ERK5 suppresses Bad expression by stimulating the transcriptional activity of CREB via RSK and by promoting the binding of CREB to the CRE sites in the bad-promoter.

In this study, we reported that a short-degraded peptide fragment 1 (derivederived from native HIV-1 envelope protein gp120-loaded rat hepatocytes, formed fibrils by self-assembly and thus enhanced HIV-1 infection by promoting the binding of HIV-1 to target cells.

Cell adhesion molecules expressed by endothelial cells can contribute to the pathogenesis of diabetic nephropathy by promoting the binding and infiltration of leukocytes.

We show here that NO links ubiquitination to sumoylation by promoting the binding of ubiquitin and SUMO E3 ligases, a process intergrating three kinds of post-translational modifications: S-nitrosation, sumoylation and ubiquitination.

Taken together these results suggest that ATM induces a direct stimulation of G6PD activity by promoting the binding of Hsp27 to G6PD.

ANP induces UCP1 expression by promoting the binding of PGC-1α and ATF2 (activating transcription factor 2) to the human UCP1 enhancer regions, and such interactions do not occur when PKG or p38 MAPK activity is inhibited.

Proteins called guanine nucleotide exchange factors, or GEFs for short, activate the Rab protein by promoting the release of GDP and the binding of GTP.

Guanine exchange factors (GEFs) activate GTPases by promoting the dissociation of GDP and the binding of GTP, GTPase-activating proteins (GAPs) inactivate the small GTPases by stimulating their intrinsic GTPase activity.

MiRNAs regulate gene expression through translational repression of mRNA by promoting the degradation of mRNA by binding to specific sequences in the untranslated regions of the mRNA.

This interaction stabilizes the activation loop and facilitates substrate binding by promoting the formation of the P+1 pocket, formed from residues that follow the activation loop.

SDF-1 promotes the growth of prostate epithelial cells by promoting the nuclear localization of AR, binding of AR to DNA and increased PSA protein in a ligand independent manner [ 52].