Sentence examples for by promoting binding of from inspiring English sources
Binding of HSP27 to AKT facilitates its phosphorylation by promoting binding of activating kinase [19].
Overexpression of Zfp467 in ADSCs inhibited Wnt signaling by promoting binding of Sost to the Wnt coreceptors LRP5/6 and disrupting Wnt induced Frizzled-LRP6 complex formation, and siRNA mediated Sost silencing reversed the inhibition of Wnt signaling by Zfp467 in ADSCs.
These suggest that LMO3 may additively interfere with the inhibitory effect of HES1 on Mash1 expression by promoting binding of HEN2 to HES1-binding sites and E-box.
The six of these which encode proteins which are critical for protein synthesis or ribosome genesis-and therefore potentially affect the titer of many other proteins-are: Fun12p/eIF5B, a GTPase which functions in translation initiation by promoting binding of Met-tRNAiMet to small ribosomal subunits and in subunit joining [14].
Gαs is known to synergize with forskolin increasing its ability to regulate cyclase activity by promoting binding of forskolin to a high affinity site (Dessauer et al., 1997).
25-HC inhibits SREBP processing by promoting binding of the SREBP cleavage activating protein (SCAP) to the endoplasmic reticulum (ER) retention protein Insig, thereby retaining the SCAP SREBP complex in the ER and preventing egress to the Golgi, the site of SREBP processing.
Deacetylated form of ChREBP is phosphorylated by PKA, which promotes binding of 14-3-3 14-3-3 14-3-3 cytosolic localization.
Although addition of PIP2-C16∗ alone does not promote complete opening of α-actinin-2, at least as measurable by DEER, it promotes binding of Zr-7 with nanomolar affinity, suggesting a positive allosteric modulation for opening and ligand binding.
Therefore, the binding and excretion of macrolide antibiotics through the biliary system is probably governed by the same factors that promote binding of macrolides to membranes, that is, in essence the hydrophobicity.
The data demonstrate that phosphorylation of this site by CK2, in response to Wnt, promotes binding of Dab2 and LRP6.
(ii) AFF4 indirectly promotes binding of the TAR RNA by stabilizing a Cyclin T1 TRM conformation that is competent for TAR binding.
