Sentence examples for by prolonged expression of from inspiring English sources
Zerumbone also significantly delayed the post-IR DNA DSB repair, as evident by prolonged expression of nuclear γH2AX foci.
Additionally, (Lee et al., 2014b) report phenotypes, similar to, but milder than those seen in FAMALGK, caused by prolonged expression of a C-terminal GFP-tagged version of FAMA (FAMAtrans).
It is tempting to speculate that this might be linked to the DNA damage response, because EPMs are observed following DNA damage induced by prolonged expression of the melanogenic genes regulated by MITF (Inomata et al., 2009), and because MITF directly regulates DNA damage repair genes in melanoma (Giuliano et al., 2010; Strub et al., 2011).
Therefore, the lethality observed in conditions of Mnn1 over-expression may be caused by the prolonged expression of Hsp70 in these embryos.
Broad polyclonal activation of T cells is detected by increased or prolonged expression of CD40 ligand, and circulating B cells with a memory cell phenotype are increased in patients [ 47, 48].
The initial deficiency in Mesp1 null embryos may be partially rescued by the later induced and prolonged expression of Mesp2.
Prolonged expression of CYCD3 1 in leaves caused by ectopic expression of ANT (Mizukami and Fischer, 2000) has led to the suggestion that CYCD3 1 is a target of ANT (Anastasiou and Lenhard, 2007; Wu et al., 2011).
Nevertheless, after prolonged expression of φC31 integrase in cultured cells, chromosomal rearrangements were found by both plasmid rescue and karyotyping [11], [13] [15].
Such strategies must promote the selective proliferation of the transplanted cells and the prolonged expression of therapeutic genes.
This suggests that prolonged expression of mutant protein is required in order to see effects.
One aspect of diabetic healing that has recently received considerable attention is the enhanced and prolonged expression of TNF- α, a potent proinflammatory cytokine [ 9].This review focuses on factors that are affected by diabetes-enhanced inflammation, particularly elevated or prolonged expression of TNF- α.
