Sentence examples for by proinflammatory agents such from inspiring English sources

The increased permeability of the blood vessels may be mediated by proinflammatory agents, such as substance P, and results in tissue oedema.

While the B2 receptor is constitutively expressed in various cell types, including endothelial cells, the B1 receptor is inducible by proinflammatory agents, such as IL-1β, in pathophysiological conditions [ 34- 36].

Upon inflammatory response, iNOS is upregulated by specific proinflammatory agents, such as endotoxin, tumor necrosis factor alpha (TNF-alpha), interferon-gamma (IFN), and interleukin-1 (IL-1) in certain cells resulting in an excessive NO production (reviewed in [100, 103 105]).

Upon inflammatory response, iNOS is upregulated by specific proinflammatory agents, such as endotoxin, tumor necrosis factor alpha (TNF-alpha), interferon-gamma (IFN), and interleukin-1 (IL-1) in certain cells resulting in an excessive NO production (reviewed in [ 100, 103- 105]).

Some proinflammatory agents, such as tumor necrosis factor- α (TNF- α), interleukin-6 (IL-6), and lipopolysaccharide (LPS), can regulate resistin gene expression.

Biochemical adaptation to these changes involves production of proinflammatory agents, such as interleukin-1β, tumor necrosis factor-α, prostaglandins, and enhanced production of MMPs, which cause matrix destruction.

Proinflammatory agents such as interleukin- (IL-) 6 and tumor necrosis factor (TNF) α, which are upregulated in CHC [ 31, 43], had no effect on chemerin mRNA and cellular and soluble protein in primary human hepatocytes (PHH) [ 41, 44].

We have designed an experimental method to assess the influence of glucose concentration on the effects of toxic agents classically involved in β-cell death and to analyze whether rat islet cell apoptosis induced by recognized islet cell toxic agents such as proinflammatory cytokines (IL-1β, TNF-α, IFN-γ) or STZ may be modulated by a pretreatment with high glucose concentration.

A key insight in the pathogenesis was the discovery of the important role played by proinflammatory cytokines such as tumour necrosis factor (TNF) [3, 4].

Their production either occurs constitutively or may be induced by appropriate stimulation with exogenous or endogenous agents, such as the proinflammatory cytokines IL-1 and TNF-α [ 13].

The inclusion of other catabolic agents, such as proinflammatory cytokines and proteinases, in such analyses may provide a better understanding of the processes occurring in the articular joint.