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"Our analysis suggests that only the lower estimates produced by previous methods are plausible," Bates said in the statement.
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Due to the fact that the placement cost of some tests at the design stage is considerably high compared with the execution cost, the sequential diagnosis strategy obtained by previous methods is actually not optimal from the view of life cycle.
All the mutations detected by previous methods were observed and there were no false positive results.
The results obtained by previous methods were compared with the results obtained by Swiss-model server for template identification (http://swissmodel.expasy.org).org
The results showed that the underestimation of HIV-1 protection rates obtained by previous method were corrected (Fig. 4B).
By contrast, previous methods were either too slow or too inaccurate on molecules with similar sizes.
One aspect of clinical relevance that had not yet been touched by the previous methods was the degree of relative negativity.
Known antibiotic resistance genes and efflux pumps described in S. maltophilia but not retrieved by the two previous methods were searched in the draft genomes by BLASTP searches after retrieving these sequences in the GenBanK database (Benson et al. 2013).
The present report focuses on the implementation and validation of the protocol; its sensitivity as compared to previous methods is shown by RACE PCR on a range of transcripts.
The distribution of respective read numbers by the previous method was 0.06% to 2.74% and the value by BeNUS method was 0.2 to 1.55%.
Isolates that exhibited clonal variation within a subject over the 12-week period or those isolates that were untypeable by either previous method were also selected for spa typing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com