It has been described that the excessive activity of either M1 or M2 subsets may be detrimental to the host by preventing the development of an efficient anti-tumor immune response.
Furthermore, inflammatory mediators might also promote the malignant transformation of epithelial metaplasia by inducing genetic and epigenetic changes and by preventing the immune system from mounting an efficient anti-tumour immune response.
These mutations were subsequently shown to contribute to increased NA activity, resulting in more efficient replication in mammalian cells, most likely by preventing the formation of virus aggregates.
Phenolic compounds are efficient free radical scavengers [ 33] exhibiting antioxidant activity by inactivating lipid free radicals, or by preventing the decomposition of hydroperoxides into free radicals [ 34].
Allowing rents to increase each year by only a benchmark of average market rents will prevent the efficient allocation of housing, creating dangerous distortions the higher the level at which the averages are calculated..
Again, targeting CSB by RNAi in these cells inhibited HCR of the UV-damaged reporter gene and prevented the efficient recovery of nascent RNA synthesis.
First, by imposing paperwork and bureaucratic second-guessing on all transactions involving foreign-exchange, the exchange controls prevented the efficient and competitive operation of any international business or charity projects.
However, flaws inherent in the technology have worked to silence activists and prevent the efficient archiving of media.
Remarkably, we found that Plk1-depletion prevented the efficient dephosphorylation of Cdh1 during mitotic exit.
Building energy efficiency standards (efficient building codes), like standards in industry, play a large role in cost-effectively reducing emissions, primarily by preventing thermal losses through the building envelope and improving the efficiency of furnaces and water heaters.
