By 5 March 2008, equipped with preliminary data obtained by the combined use of optical rotation, capillary electrophoresis (CE), and H NMR, the FDA announced that the contaminant was a "heparin-like" molecule.
The sample size was determined by power analysis using preliminary data obtained in our laboratory.
In the present study, preliminary data obtained by PCR-RFLP indicated the co-infection by other species [ 34].
"Preliminary data obtained by MedPac indicate handling charges could be as much as 26% to 28% of drug costs (remainder are acquisition costs).
Preliminary data obtained by EMSA showed that nuclear extracts from untreated Raji cells had a basal level of AP-1 DNA-binding activity and p17 activated AP-1 DNA-binding activity in a dose-dependent manner with a peak at 1 µg/ml dose (data not shown).
Our preliminary data, obtained by in vitro and in vivo experiments using MDA.MB231 breast cancer cells, seems to validate this hypothesis (Bimonte et al., unpublished data).
The recommended dose of oseltamivir for g lomerular filtration rate <30 mL/mis/1.73 m is 2 3 mg/kg/day, based on preliminary data obtained by a National Institutes of Health funded Collaborative Antiviral Study Group (10 ).
Preliminary data obtained by quantitative FACS analysis with MAb 16A11 directed against MAR3-MBP indicates that human malignant glioma cell lines T98G, D247 MG, and D54 MG express 0.3-4.9 0.3-4.9RP3 molecules per cell.
However, preliminary data, obtained by analyzing the same samples using L. iners specific realtime PCR, indicate that for most women for which this species could be isolated by culture from the vagina, also the rectal sample is L. iners PCR positive (data not reported).
Preliminary data obtained by exposing monocyte-derived DCs to all the drugs used against PEL cells, at the concentrations able to reduce 50% of PEL cell survival, showed that all of them, except for Bortezomib and Bay11-7082, were almost completely safe towards DCs (data not shown).
