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These patterns are caused primarily by positive selection, so our scan missed other types of selection.
This suggests that some of the allele replacements were driven by positive selection so weak (Watterson 1975) that the ancestral allele is present in the sample of 37 genotypes, albeit at a low frequency.
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A major focus of modern population genetics involves using polymorphism data in order to identify regions impacted by recent positive selection (so-called genomic scans).
Other genes involved in the response of organisms to their immediate environment have sometimes been shown to be driven by positive selection [ 12- 16], so called "arms races" [ 17].
Approximately 20% amino acid changes between chicken and zebra finch have been fixed by positive selection [ 8], so by comparing coding sequences (CDS) between these birds, chicken genes with signals suggestive of adaptation can be identified.
However, this value was much lower than the FI value of the human accelerated gene set (FI = 1.68), indicating that they are not so influenced by positive selection as the latter set.
On the other hand, Wellmer and collaborators [55] suggested that the functional redundancy during early flower development may have increased the genetic buffering so that duplicated genes are retained by positive selection.
If the nonsynonymous mutations are favored, the nonsynonymous rate should be higher than synonymous, and so ω > 1 indicates evolution by positive selection.
It seems that sites within the triple beta-strand so characteristic of these peptides are largely unaffected by positive selection.
Genes that have been changed by positive selection have significantly more protein-altering mutations.
We infer that this young haplotype has been driven to a high frequency by positive selection.
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