Bone is a slowly regenerating tissue influenced by various physiological processes, including proliferation, differentiation, and angiogenesis, under the control of growth factors.
They play an integral part in the human signaling pathway by regulating various physiological processes including cell growth, differentiation, adhesion, motility, and apoptosis [46].
Cell death plays a fundamental role in animal development and tissue homeostasis by modulating numerous physiological processes, including regulation of cell number and organ size, sculpting of tissue structures, and elimination of abnormal or aged cells.
The synthesis of hepcidin is regulated by diverse, often competing, physiological processes, including iron stores, inflammation and erythropoietic drive (Ganz, 2011, Atkinson et al., 2014).
The proteosome inhibitor bortezomib exerts anti-tumor activity by affecting a number of physiological processes, including preventing degradation of pro-apoptotic factors.
Purinergic signaling by extracellular ATP plays roles in diverse physiological processes including cell proliferation, development, neurotransmission, and motility.
MMPs are physiologically cleaved by tissue inhibitors of metalloproteinases (TIMPs) and are involved in physiological processes including tissue remodelling, but also in pathological processes when their balance is disturbed.
Growth hormone (GH) is synthesized and released by the anterior pituitary gland to regulate multiple physiological processes including growth and metabolism.
Over half of known proteins are modified by covalently bound glycans, which are important for physiological processes including protein folding, degradation, signaling, and immune function [ 33].
However, this assumption is still speculative since additionally to water uptake, aquaporins are involved in many physiological processes including stress responses also induced by CNTs and therefore, more detailed investigation of the involved aquaporin genes is necessary.
