Sentence examples for by persistent changes in from inspiring English sources
Another medical reason is that cancers are nearly always caused by persistent changes in a person's DNA (which, as it happens, often cause mayhem in the epigenetics of their cells: the cancer's cellular memory goes haywire).
Osteoclasts, cells responsible for bone resorption, contribute to the development of degenerative, metabolic and neoplastic bone diseases, which are often characterized by persistent changes in bone microenvironment.
AMPA receptor expression at synapses is regulated to modify synaptic efficacy in the context of long-term potentiation (LTP) and long-term depression (LTD) (Song and Huganir, 2002), as well as homeostatic control of synaptic function driven by persistent changes in neuronal activity (Turrigiano, 2008).
Together, our findings indicate that we may have identified a novel form of epigenetic regulation, which could be termed "lactational programming," characterized by coordinated and persistent changes in gene expression during and after increased milking frequency.
However, the cellular targets and mechanisms by which developmental exposures cause persistent changes in the function of the immune system are unknown.
The mechanism by which developmental exposures lead to persistent changes in immune function is unknown, yet modifications to immunologically based processes have been reported to occur (Winans et al. 2011).
However, our results are consistent with a model of persistent changes in DNA methylation induced by TGF-β.
There were no clinically significant or persistent changes in lung function tests performed by spirometry.
Persistent changes in synaptic strength are locally regulated by both protein degradation and synthesis; however, the coordination of these opposing limbs is poorly understood.
Subsequent changes in myelin might emerge as relatively smaller, persistent changes in other quantitative MRI64,65,66.
In contrast, persistent changes in the microstructure after different shear treatments have been observed.
