While localization accuracy can be improved by using a high resolution spatial grid and a high number of microphones, performing the localization task in these circumstances requires a high computational demand.
On the contrary, the proposed tracking strategy can track the parameters firstly and then perform the localization by trilateration.
Alan Prescott supervised and performed the localization studies.
DS installed the localization algorithms, performed the localizations and participated in the design of the study.
This simplification can be justified by performing a localization procedure, using a finite covering Ω ¯ ⊂ ⋃ k = 1 N U k with appropriate open sets U k, a corresponding partition of unity and perturbation results.
Subsequently, we focused on the localization of the sorLA-FANSHY→6A by performing co-localization studies between non-mutated sorLA (sorLA-WT) and sorLA-FANSHY→6Awithin the same cell.
By performing a single distance estimate in the localization process (Fig. 12(c)) and using a three-beacon structure, the tracking results with Kalman and Particle filters are very close.
We further confirmed these data by performing voxel by voxel co-localization analysis on 3D images to generate a Mander's Overlap Coefficient (MOC), which is a quantitative measure of co-localization (Chang et al., 2013).
By performing co-immunoprecipitations and studying subcellular localization, we validated the interaction of LET-756 with RPS-16, FTT-1/PAR-5, FTT-2, KIN-10 and RPL-6 with high score, and with PAL-1, DAF-21, SKR-2, KIN-3 and C18A3.3 with lower strength (see Table 6).
