Sentence examples for by pathways shown in from inspiring English sources

In order to understand the molecular mechanism of MAA-induced growth arrest of normal human fibroblasts, we hypothesized that MAA may induce ROS resulting in oxidative damage to DNA and mitochondria, and that in turn induce DNA damage signaling and loss of mitochondrial membrane potential culminating in growth arrest of cells by pathways shown in Figure 2A.

IMP is not present in the cells under normal conditions and is converted to adenine, xanthine, and guanine nucleotides by the pathways shown in Figure 2.

All such tracts can be explained as the consequence of the repair of one or two broken chromatids by one of the HR pathways shown in Figure 1.

Furthermore, we built up a network composed of hubs and signal pathways shown in Figure 5, by which we found that mDHs are more likely to be the connectors among signal pathways.

Butyrate biosynthesis in clostridia is believed to proceed by the pathway shown in Fig.  1.

The formation of products 12 can be rationalized by the pathway shown in Scheme  5.

The cleaved products do not resemble a result of tRNA degradation by the nuclear surveillance pathway shown in yeast, where defective tRNAs are at first polyadenylated, followed by exosome processing [ 58, 59].

These genes code nuclear hormone receptors involved in the control of developmental and physiological pathways shown to be activated by BPA in laboratory studies.

Importantly, while these pathway signatures have previously been validated [ 2], the model by model pathway predictions shown in Table  2 are highly consistent with previously published tests.

Moreover, the analysis indicated that the 'acute-phase response signaling' canonical pathway was most significantly affected in the R group, followed by the complement and coagulation pathways, as shown in Figure 3.

In addition, our cDNA array analysis revealed that genes that are known to be regulated by these pathways show very similar expression patterns in ciNPCs and control NPCs, which are significantly different from that in MEFs, further supporting the idea that activation of a defined set of genes by these pathways in concert are critical for the successful transition of MEFs to NPCs.