ER homeostasis can be perturbed by pathological processes such as hypoxia, glucose deprivation, viral infections, environmental toxins, inflammatory cytokines, and mutant protein expression, as well as by physiological processes such as aging.
These proteolytic enzymes and their control mechanisms are known to be exploited by pathological processes, such as cancer dissemination, which ultimately lead to destruction and loss of function of the tissue architecture.
Thus, these biomarkers performed with different effectiveness when evaluated by individual pathological processes such as necrosis, apoptosis, and regeneration.
Pathological processes such as LV remodeling will be examined by comparison to pathology-matched statistically predicted parameters, based on an individual's known clinical characteristics and the CAP population subgroup he or she matches most closely.
Activation of these channels by protons plays an important role in physiological and pathological processes such as nociception, mechanosensation, synaptic plasticity, and acidosis-mediated neuronal injury [3].
Besides its normal role in e.g. sexual development and reproductive function, the estrogen receptor is involved in several pathological processes such as breast cancer (as reviewed by Dahlman-Wright et al. 2006 [ 20]).
In addition to its function as a regulator of adipocytes differentiation, PPARγ is expressed by several other tissues, and is involved in a number of pathological processes, such as inflammation and cancer [50].
TACAs, in general, are involved in many biological and pathological processes, such as regulating cellular and molecular interactions by either masking recognition sites or serving as recognition determinants [ 4].
These effects are linked to a number of pathological processes such as atherosclerosis, diabetes, neurological disorders and pulmonary dysfunction [3].
Functional imaging is increasingly used to assess underlying pathological processes such as neuroinflammation and abnormal protein deposition.
Pathological processes such as cancer induce profound changes in the nuclear architecture, which also affects telomere dynamics and spatial organization.
