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Our objective was to test the hypothesis that reducing insulin secretion by partial disruption of the Ins2 gene would prevent diet-induced obesity.
In order to induce production of antibodies, protein must be exposed so that it can be recognized by B cells and this might happen by partial disruption of VLP membrane with exposition of antigen and direct stimulation of B cells.
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There are several possible causes of the flares: a short-lived jet produced by the partial disruption of a star by Sgr A*; the ripping apart of a planet by Sgr A*; the collection by Sgr A* of debris from close encounters between two stars; and an increase in the consumption of material by Sgr A* because of clumps in the gas ejected by massive stars orbiting Sgr A*.
Social motility was also triggered by physical agitation or partial disruption of previously undisturbed developing SL-biofilms (see Additional files 5, 6 and 7: Movies 4, 5 and 6).
Subclinical and clinical inflammation is usually characterised by increased expression of cytokines, influx of inflammatory cells and partial disruption of the epithelial barrier as defined by downregulation of epithelial junction proteins.
Importantly, their results help to explain previous results from the same and other groups regarding the partial disruption of CTA memory by some pharmacological interventions.
As shown in Figure 6A, a well resolved signal (Ha) was obtained after partial disruption of mycobacterial cell wall by adding 5 µl of chloroform to cell pellets directly into the Zr rotor.
Addition of 0.75 μmol/l colchicine to intact cardiomyocytes induced a partial disruption of SR mitochondria interaction, confirmed by both decreased RyR VDAC immunocolocalization and reduced number of amplification clusters in PLA assay.
This could be explained by assuming the stem-loop-stem structure causes at least partial disruption of the IRES secondary structure.
By introducing osteoarthritis-like degradation via MMP-13, we found partial disruption of collagen structure leads to significant increase in aggrecan collagen adhesion.
Analogous to the mislocalization of GFP-OEP7, these OEP9-GFP-containing punctate structures likely represent mislocalized aggregates of the fusion protein due to the partial disruption of the OEP9's plastid targeting information by the appended GFP moiety.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com