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Concordance of methylation between family members with CS was calculated with Kendall's coefficient of concordance by pairwise analysis between proband and first- and second-degree relatives.
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Incidences were generally assessed by Chi-square test, followed by pairwise analysis with Bonferroni correction.
Statistically significant differences in pairwise analysis between all generated groups are presented in Table 2b.
Genes co-expressed with DCN were identified by pairwise correlation analysis between expression profiles of DCN and each other gene measured by the Affymetrix microarrays, using the Pearson's rank correlation coefficient.
In contrast, AMOVA based on nuclear microsatellite loci revealed no overall genetic differentiation between populations in the two Bays (Table 2, differentiation by site), although pairwise analysis did indicate marginally significant differentiation between Dokai Bay and one Tokyo Bay site (Table 3).
We ran the pairwise analysis by including only certain transmissions.
An additional technical validation was done by performing a pairwise correlation analysis between the miRNA profiles obtained by qRT-PCR and the nCounter Analysis System for the 12 samples analyzed on both platforms.
Epithelial membrane protein 1 (EMP1), discoidin domain receptor 1 (DDR1) and human homolog of the Drosophila dishevelled gene (DVL1) were found by pairwise comparison analysis to be differentially expressed between lobular and ductal carcinomas.
Hence, to determine network reproducibility, we performed a pairwise analysis and determined the overlap between the modules produced by the two contrasting methods.
Putative orthologs between species were identified by pairwise BLASTP analysis (E-value: 1e-6; min. hit coverage 70%%) and aligned using the software ParaAT [ 59].
Pairwise analysis is represented by a, b where p < 0.05 versus nativea, and acetylcholineb.
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