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In this way, we can assist to investigate the mechanism of combination drugs by our simulation result.
As suggested by our simulation result (Fig. 9) in Section 5, the increased δ p value in TSA-treated cells is attributed to chromatin decondensation and the increased correlation length [ 31] due to TSA-induced histone acetylation.
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The effectiveness of the proposed approach is verified by our simulation results showing disturbance rejection of 62% and perfect disturbance elimination, as well as by our experimental results showing disturbance rejection of 54%.
Therefore, Hypothesis 1 is not supported by our simulation results.
This is illustrated by our simulation results as shown in Fig. 3b.
This result is also supported by our simulation results in Figure 4D.
This is corroborated by our simulation results.
This expectation is confirmed by our simulation results.
This rationale is supported by our simulation results.
This hypothesis, originally formulated by Fisher (1930) and Muller (1932), is corroborated by our simulation results in Figure 4A.
To account for these issues, we took the conservative approach suggested by our simulation results by modeling the population size to be constant and at 1 million individuals.
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