The grain boundary precipitation mechanism of perovskite phases suggested by our simulations is through the extraction of Cr atoms from the oxide scale.
In this context, it is not surprising that the seemingly minor effect of ligand binding on the conformation of domain II in the heterodimerization partners of Her2 demonstrated by our simulations is of great importance to the regulation of Her2 activity.
The increased stability and high folding rate predicted by our simulations were subsequently validated by temperature-jump experiments.
All huts around the summit area of Mount Ontake are made of wood, and the energies estimated by our simulations are much larger than the critical energy required to penetrate a wooden roof.
It is important to stress that the microdomains of high Ca2+ predicted by our simulations are not generated by assuming non-uniform distributions of Ca2+ channels, pumps, or Ca2+ release sites or by proposing new molecular properties for Ca2+ channels.
The CIs obtained by our simulations were comparable to those calculated after Li, albeit the latter were usually slightly wider.> -wrap-foot> chromosomesome; logP = negative 10-base logarithm of P value; Sig = genome-wide significance level; 99th % threshold logP = threshold used to define cut-off for QTL peaks (Fig. 4); Hr = regional heritability.
Our simulation is conducted by using Qualnet 5 network simulator (Los Angeles, CA, USA) [28] with at least ten experiments conducted for each scenario and each algorithm.
The relatively low yield in the distantly related data set as compared to our simulation is consolidated by observing that Orkney has had a stable population size for an extended period of time, resulting in well-mixed recombinant haplotypes.
Consistent with these findings, we observe that the transition to the inward-facing state in our simulations is accompanied by the spontaneous release of the Na+ ion from the Na2 site.
We furthermore investigated the responsiveness of the system predicted by the model with respect to the total amount of stimulus provided (Epo tot ), which in our simulations is represented by the product Epo tot = Epo tr · T Epo (Sup. Mat. A4 contains further explanations [see Additional file 1]). Figure 6 shows our results, which condense the information depicted in Figure 5.
