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Three studies were considered to be low quality, and 34 were considered moderate to high quality by our scoring system (Additional file 3: Table 3S).
This feature would be well reflected by our scoring system - either increasing the overall AFI or decreasing the variance within the same group favored a −log[p] score (or a low p-value).
Although benefit of screening may not be clearly seen at the moment due to uncertainties of the true liver condition (whether it is a simple steatosis or a NASH); in our opinion, individuals with higher fatty liver scores calculated by our scoring system should be advised regarding more healthy living habits such as calorie restriction and exercise.
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This confirms that the ranking computed by our gene scoring system is significantly different from a random ordering.
Indeed, the only prerequisite for a gene to be prioritized by our gene scoring system for a given disease is that of being annotated with at least one GO term, but, as clearly evidenced in this study, we are still far from the complete annotation of the entire human genome, as we were forced to exclude almost half of the possible candidates since they completely lacked GO annotations.
This weak association with OA symptoms may also be related to the limited number of articular features assessed by our MRI scoring system.
Logistic regression analysis of data from this present study supports this view, suggesting that more selective assessment of patients destined for a level 1 care environment may be possible by placing greater weight on physiological score and urgency rather than nature of operation and by utilizing our proposed scoring system S-POSSUM.
Aiba has defended its referees and judges, claiming that under the "10-points-must" scoring system introduced for these Games, in place of the old round-by-round scoring system for punches landed, the best boxer is rewarded.
In this study, we assessed the reliability of our new scoring system by evaluating inter-rater agreement.
Therefore, it is not possible to make realistic outcome comparisons between transferred and non-transferred patients by using our standard scoring systems [ 32, 33].
Our data are consistent with their findings and extend their findings by providing a scoring system, by analysing the potential relationship between K8 staining and butyrate, and by cross-validating the data with a second independent methodology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com