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Recently, a study by our group, utilizing a high throughput mitochondrial sequencing array for the entire mitochondrial genome has demonstrated a 49% of incidence of mitochondrial mutation in head and neck squamous cell carcinoma in another limited cohort [27].

An analogous AP-MS study in mouse ES cells by our group, utilizing a mammalian affinity purification and lentiviral expression (MAPLE) system, was used to identify a novel link between the Klf4 reprogramming transcription factor and the chromatin-remodeling machinery that is required for efficient induction of pluripotency [ 66].

Interestingly, recently published data by our group utilizing murine models of infection and trauma do not completely support this severely exacerbated gene expression pattern in mice of advanced age, although restoration of genomic homeostasis is certainly delayed [ 10, 11].

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A functional model developed by our group utilizes a picosecond laser at a wavelength of 532 nm.

For the detection of NY-BR-1, mAb NY-BR-1 5 previously geNY-BR-1 5y NY-BR-1 5 was utilized [ 23].

Increased appreciation for the intimate link between kinases and health has prompted the development of technologies to characterize the phosphoproteome or kinome [ 11], including efforts by our group to utilize peptide arrays for low-cost, high-throughput kinomic characterizations [ 12- 16].

In a second study by the same group, utilizing ATR-FT-IR to investigate blood plasma from ovarian cancer and endometrial cancer patients, a classification (up to 96.7%) was achieved for the former, whereas for endometrial cancer an accuracy (up to 81.7%) was achieved by use of a support vector machine.

A scaffoldless approach to tissue engineering, the self-assembly process, has been developed and utilized by our group to produce engineered constructs with biochemical and biomechanical properties approaching native tissue values [3], [19], [20].

In previous studies by our group, negatively-charged nanoparticles were utilized to coat the positively-charged Tat (1 72 aa) on the surface of the nanoparticles by charge interaction.

This analysis serves as an example that will inform ongoing efforts by our group and others to construct and utilize exposure prediction models that are most suitable for epidemiologic studies.

A similar conclusion was reported by our group when a steroid-avoidance immunosuppression regimen was utilized for low-risk live-donor transplant recipients [ 3].

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