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As show by our functional data, these three CD56dim subsets display the same ability to degranulate against HLA-I− targets.
This hypothesis is further reinforced by our functional data showing that 3'UTRs of both human and mouse Mmp-15 and -24 are similarly targeted by miR-29b and -29c.
This latter event predicts slower progression through S phase and this is validated by our functional data.
However, the prediction that flows from the O'Connell hypothesis -- that IL4 variants differing in positively selected residues would bind with differential affinity to IL4Rα -- is not borne out by our functional data.
While only a small number of SOD1-related ALS cases with a range of post-mortem intervals have been sampled, the pathways implicated have been supported by our functional data and evidence in the published literature.
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By integrating our functional data with publicly available gene- and protein-interaction data, we determine networks of functionally related genes that control cytokinesis, cell growth, and differentiation in the Drosophila brain.
A mechanistic basis for our behavioural findings is provided by our functional MRI data, which specifically addressed the neural representation of stimulus value during the performance phase.
These observations are supported by our previously reported functional data from CDC1551-infected rabbits [ 15].
Hybrid PET/CT device allows enhanced detection and characterization of neoplastic lesions, by combining the functional data obtained by PET with morphological data obtained by CT [ 4].
Metabolomics has also enriched genome-wide association studies (GWAS) in this area by providing functional data.
However, the authors' discussion and interpretation of gating mechanism is, in general, not well substantiated by the functional data that accompanies presentation of the structure, and this will require revision.
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