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These results are further confirmed by our analysis using U.S. data.
Our analysis using VBM indicating reductions in anterior amygdala volume was corroborated by our analysis using SBM.
One of the functions suggested by our analysis using the SKB involves co-transcription of an IG with one of its adjacent genes in order to prevent binding of transcription factors regulating the other adjacent gene.
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This "common primer" explanation is given weight by the results of our analysis using different density thresholds and the less compelling results given in the Cote d'Ivoire study for children selected on less stringent clinical criteria, who may have had lower parasite densities.
Since health-state values have been shown to be affected by the number of health states valued by a respondent, we repeated our analysis using only the first five valued health states [ 16].
These translocation events would not be detected by our FISH analysis using centromeric probes.
Thus, the pooled RR of 1.44 reported in the meta-analysis may be a systematic underestimate of the true magnitude of the association, which is supported by our secondary analysis using all nonsmokers as the reference group (1.50 [1.50–1.50]).
We also tested one of the potential roles of TIMELESS suggested by our network analysis using a MTS assay and observed that TIMELESS knockdown decreased the proliferation rate of MCF7 breast cancer cells.
By our PCR analysis, using primers that distinguish deletion-bearing and intact mitochondrial genomes, no major apparent differences in heteroplasmy levels exist between AF16, HK104, and the five cybrid lines.
While drug resistance patient tumor samples are needed to further validate the role of SMARCE1 in modulating drug responses, the regulation between SMARCE1 and EGFR signaling is likely hard-wired as suggested by our correlation analysis using the large number of lung patient tumors.
We address this limitation by automating our pathway analysis using queries to the well-known Gene Ontology database.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com