We therefore cannot exclude that nucleosomes released into the circulation by other cell types, such as endothelial and parenchymal cells, are detected as well.
These biologically active molecules, synthetized by the injured tissue or by other cell types present at the inflammatory site, are release in the extracellular space and modulate the regenerative response (Table 1).
To determine which of the expressed genes are innate to keratinocytes, which are specific for the differentiation and 3-D architecture, and which are induced by other cell types, we compared the transcriptomes of skin from human subjects, differentiating 3-D reconstituted epidermis, cultured keratinocytes, and nonkeratinocyte cell types.
Once the antibodies bind to the various killed or attenuated viruses within the vaccine, they are marked for destruction by other cell types.
In addition, Stamp et al did not detect IL-17 production by other cell types [12].
Only the Nav1.2 isoform was found in the intact media and in freshly isolated myocytes excluding contamination by other cell types.
Reciprocal influences between effector and regulatory cells are also influenced by other cell types and involve both soluble factors and cell-to-cell interactions.
Proteins such as Nestin, Musashi, Sox2, and glial fibrillary acidic protein (GFAP) are expressed in neural precursor cells [6] [9], but they are also expressed by other cell types.
Although neutrophils appear to be the predominant source of IL-17A, we cannot conclude that increased IL-17A production by other cell types in response to C. neoformans strain H99γ infection does not contribute to the observed phenotype.
In addition, we did not mince donor muscle before enzymatic digestion (see Methods), which is advantageous for cell isolation with minimum contamination by other cell types, such as committed ECs.
Also stroke has been shown to result in decreased proinflammatory cytokine secretion by other cell types such as macrophages resulting in the net-decrease of serum cytokines despite enhanced T-cell activation [6].
