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It has been well documented that marked changes in intensity may be accompanied by only small changes in prevalence [ 35- 37].
Binding of the second mole of UP1 to the UP1 Tel-22 Na+ G-quadruplex complex is accompanied by only small changes in the CD spectrum.
In light of our goal to produce a useful and usable annotation set, we are reluctant to create gene models with many alternative transcripts that differ by only small changes in the 5′ UTRs.
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Increasing or decreasing any of the model parameters by 10% resulted in only small changes in the outcomes assessed in the sensitivity analyses.
This finding is in good agreement with previously reported data, which suggests that most of the iron uptake by lactoferrin occurs within a few seconds, followed by a very slow reaction giving only small changes in absorption at 466 nm [ 50].
The V207A substitution caused only small changes in catalysis by ADH since both steady-state and transient-state kinetics were similar to those of the wild-type enzyme.
It is specifically adapted to the older hospital population and setting although only small changes were deemed necessary by the reviewers.
The corrections of GPA by the higher order terms of cumulant expansion introduce only small changes to the tail of spin echo decay.
In both cases, the distributions for different system sizes have only small changes which can be accounted for by noise.
Only small changes were observed when W146 was exchanged by tyrosine except an increase in the bond length between H160 and the heme iron.
Consequently, small changes in structure often cause only small changes in activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com