by only sequencing the

USAGE SUMMARY

The phrase "by only sequencing the" is correct and usable in written English.
It can be used in contexts where you are specifying a method or limitation related to sequencing something, often in scientific or technical discussions. Example: "We were able to identify the genetic variations by only sequencing the exons of the DNA."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

2 human-written examples

This sequencing method reduces the genome complexity by only sequencing the DNA fragments with restriction sites.

BMC Genomics

The RenSeq experiment was carried out on genomic DNA, to facilitate the reannotation of the full NB-LRR complement, and in addition on double-stranded cDNA, to test if the complexity of sequencing data for this multigene family can be further reduced by only sequencing the expressed genes.

BMC Plant Biology

Human-verified similar examples from authoritative sources

Similar Expressions

58 human-written examples

Sequencing of reduced representation library (RRL), which further reduces the sequencing cost by only sequencing representative parts of the complex genome, can rapidly detect thousands of SNP loci [ 23].

BMC Genomics

Only by sequencing the most primitive animals can we discover those genes that are uniquely "animal" and provide an outgroup for an analysis of their evolution.

Yale University

It is important to note that this finding can only be proven by sequencing the complete miRnome of normal gastric mucosa.

Bioinformatics and Biology Insights

For each fly line only sequences generated by the Illumina platform were used.

BMC Genomics

Rule-based classifiers have been successfully used in the analysis of aligned sequences, e.g., in [ 59] and [ 60], where the classification of biological sequences to their species is performed by considering only sequences from the same gene region.

BioData Mining

When transcripts were represented by only one sequence, the EST was referred to as a 'singleton'singleton

Plosone

Homologous strawberry sequences were further analysed by the BLASTx algorithm, and only sequences showing the highest sequence homology with the corresponding Arabidopsis genes were included in real-time RT-PCR analysis.

BMC Plant Biology

Testis-specific genes were selected by using only sequences from libraries where the tissue type included the keyword "testis" and not the keyword "embryo".

BMC Genomics

In terms of distribution, the MoeB structure (146 sequences) was much more common than the MoeBR structure (12 sequences), while MoeZ was represented by only six sequences in the GenBank non-redundant (nr) database.

BMC Evolutionary Biology

Expert writing Tips

Best practice

When describing research methodologies, clarify the rationale behind limiting sequencing efforts to specific regions or elements. This enhances the transparency and reproducibility of your work.

Common error

Avoid stating that "by only sequencing the..." you are comprehensively analyzing the entire genome. Clearly define what information can and cannot be inferred from your limited sequencing scope.

Linguistic Context

The phrase "by only sequencing the" functions as a prepositional phrase that modifies a verb, indicating a method or limitation in how sequencing is performed. Ludwig AI confirms its grammatical correctness.

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "by only sequencing the" is a grammatically correct prepositional phrase commonly used in scientific literature to describe a selective approach to DNA sequencing. Ludwig AI indicates that it is correct. This method is employed to reduce costs, simplify analysis, or target specific regions of the genome. While it's a valid strategy, be aware of potential biases and limitations when interpreting the results, and clearly define the scope of your analysis. Consider alternative phrases like "through selective sequencing" or "via targeted sequencing" for clearer communication.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

by exclusively sequencing

Emphasizes the exclusivity of the sequencing process.

sequencing only selected regions

States that just certain parts are subject to sequencing.

via targeted sequencing

Highlights that sequencing is directed towards a specific target.

through selective sequencing

Focuses on the action of sequencing being selective by design.

focusing sequencing efforts on

Highlights the allocation of sequencing resources to a particular area.

using restricted sequencing methods

Implies the application of methods that limit the scope of sequencing.

with limited sequencing scope

Directly indicates a defined boundary for the sequencing effort.

through narrow sequencing

Describes a sequencing approach that is confined to a specific area or purpose.

by sequencing a subset

Emphasizes the use of a portion of the material for sequencing.

employing sequencing sparsely

Conveys that sequencing is used in a minimal or infrequent manner.

FAQs

How can I phrase "by only sequencing the" in a simpler way?

Consider using phrases like "through selective sequencing", "via targeted sequencing", or "sequencing only selected regions" for conciseness.

What does it mean to analyze data "by only sequencing the" protein-coding regions?

It means you are specifically focusing on the exome, which contains the genes that code for proteins, while ignoring other parts of the genome. This can be more cost-effective but provides less information about non-coding regions.

When is it appropriate to use "by only sequencing the" instead of whole-genome sequencing?

It's appropriate when you have specific targets of interest, need to reduce costs, or want to increase sequencing depth for particular regions. Whole-genome sequencing is better for comprehensive discovery.

Is there a risk of bias introduced "by only sequencing the" most accessible DNA fragments?

Yes, there can be. Techniques like Restriction-site Associated DNA sequencing (RAD-seq) can introduce bias because they target specific restriction enzyme sites. Be mindful of this potential bias in your analysis and interpretation.