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The change from one climatic regime to another was caused by only modest changes in the pattern of insolation within the Holocene interval as well as the interaction of these patterns with large-scale climate phenomena such as monsoons and El Niño/Southern Oscillation (ENSO).
This is reflected by only modest changes in peak velocity, stroke volume, and cardiac output between days two and five.
Indeed, knockdown of OTX2 resulted in a decrease in cell growth and revealed a novel role for OTX2 in regulating self-renewal of human cells; however, this was accompanied by only modest changes in hESC gene levels that are already elevated in these cells.
It can significantly increase blood glucose at high doses, but recent studies demonstrate that at modest doses (750 2,000 mg/day), significant improvements in LDL cholesterol, HDL cholesterol, and triglyceride levels are accompanied by only modest changes in glucose that are generally amenable to adjustment of diabetes therapy (266, 267).
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The United Stated Department of Agriculture identified a potential 1.3 billion oven dry tonnes (odt) per year from US forestry and agriculture by the mid-21st century, requiring only modest changes in land use, agricultural and forestry practices [ 3].
Certainly not the small dietary changes recommended by government agencies and other organizations -- these are only modest changes to the average American's diet, and the average American starts developing heart disease during childhood.
With heavy lobbying by business groups, many progressives feared the White House would recommend only modest changes, thereby impacting relatively few workers and employers.
That's at the heart of what it means to be middle class in America". With heavy lobbying by business groups, many progressives feared the White House would recommend only modest changes, thereby impacting relatively few workers and employers.
Generally, these structures have indicated that only modest changes in the conformation of FKBP12 are induced by these binding interactions.
Here only modest changes occur in the stress-strain curve.
In contrast, there were only modest changes in all genotypes using the delayed treatment paradigm.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com