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We downgraded all the studies reviewed by one level for indirectness of population based on geographic location since they included little or no data from African children.
The evidence can be downgraded from 'high quality' by one level for serious (or by two levels for very serious) limitations, depending on assessments for risk of bias, indirectness of evidence, serious inconsistency, imprecision of effect estimates or potential publication bias.
Several studies showed high risk of attrition bias and performance bias dWe rated down the quality of evidence by one level for significant unexplained heterogeneity (P < 0.00001, I 2 = 82%) eWe rated down the quality of evidence by one level for significant unexplained heterogeneity (P = 0.02, I 2 = 60%).
The CI included both significant benefit and small harm, but the number of events was not small cWe rated down the quality of evidence by one level for risk of bias.
Bortezomib was dose-reduced by one level for neuropathy.
Since the studies were conducted among predominantly non-African populations the quality of evidence was downgraded by one level for indirectness.
Similar(43)
The Moody's change came after Fitch Ratings downgraded by one level the debt ratings for WPP.
Health state descriptions are constructed by taking one level for each attribute (e.g., 11111 represents the highest health status).
Health-state descriptions are constructed by taking one level for each attribute, thus defining 243 (3) distinct health states ('11111' represents the best health state).
* Fuzzy overestimation by one level.
An individual health status is described by an eight-element vector, with one level for each attribute.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com