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Dopamine receptor mediated signaling is extensively regulated by numerous processes, including, endocytosis, whereby agonist activated receptors are rapidly silenced by removal from the cell surface to an endocytic compartment.

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Prostaglandins are lipid molecules regulating numerous processes including modulation of immune function [1] [3].

TGF beta is a potent regulator of numerous processes including haematopoiesis, cell proliferation, differentiation and activation.

Moreover, CLU may play a role in numerous processes, including autoimmunity, inflammation, and immunological activities [ 8].

Reactive oxygen species (ROS) are ubiquitous in the intracellular environment and are generated by numerous endogenous processes including, for example the mitochondrial electron transport chain, reviewed by Murphy [1].

2,3,7,8-Tetrachlorobenzo- p-dioxin (TCDD), a halogenated compound that binds the aryl hydrocarbon receptor, is a by-product of numerous industrial processes including waste incineration.

Cell death plays a fundamental role in animal development and tissue homeostasis by modulating numerous physiological processes, including regulation of cell number and organ size, sculpting of tissue structures, and elimination of abnormal or aged cells.

Berry development is characterized by changes in numerous biological processes, including cell division and enlargement, primary and secondary metabolism, and resistance or susceptibility to abiotic or biotic stresses [ 3, 4].

Post-transcriptional modification by SUMOylation is involved in numerous cellular processes including human spermatogenesis.

Modification of proteins by ubiquitination is a fundamental mechanism for regulating numerous cellular processes including DNA repair, cell cycle regulation, antigen presentation, cell-cell communication, cell differentiation and apoptosis.

miRNAs are small noncoding RNA molecules on average 22 nucleotides in length that regulate numerous biological processes including cancer pathogenesis and mediate gene down-regulation by targeting mRNAs to induce RNA degradation and/or interfering with translation.

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