Sentence examples for by nucleolytic processing of from inspiring English sources

This ssDNA is generated by nucleolytic processing of DSB or arises from perturbed replication.

HR is initiated by nucleolytic processing of the DSB end to generate 3' ssDNA (single-stranded DNA) overhangs.

Biogenesis of C/D box snoRNAs is a complex process that involves posttranscriptional snoRNP assembly coupled with nucleolytic processing of host gene pre-RNA introns and intranuclear trafficking (Filipowicz and Pogacic 2002).

Thus, Mre11 nuclease activity is required for the nucleolytic processing of the HO-induced telomere in G1 cells lacking Rif2.

Early in homologous recombination, the nucleolytic processing of DNA double-stranded (ds) breaks or single-stranded (ss) gaps formed during replication produces a stretch of ss DNA that is targeted by recombinases and subsequently paired with a homologous duplex to form a DNA joint called a D-loop [2].

Yku-mediated inhibition of Exo1 is relieved in G2, as nucleolytic processing of an HO-induced telomere in G2-arrested rif2Δ cells depends on both Mre11 nuclease activity and Exo1 even when Yku is functional (Figure 3).

Biogenesis of miRNAs involves nucleolytic processing of a precursor transcript with extensive foldback structure [ 21- 23].

Nucleolytic processing of the template DNA strand should stop transcription of the corresponding gene.

MRN/X is also implicated in nucleolytic processing of telomeres to generate G-overhangs [95,96].

Besides snR30, the nucleolytic processing of eukaryotic rRNAs also requires the U3, U8, U14 and U22 box C/D snoRNAs.

Here, we identified BRCA1, CtIP and EXO1 as novel activities required for nucleolytic processing of telomeres lacking TRF2.