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We then converted these to yields by normalizing the fluxes to the area of influence (see methods).
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By normalizing the sampler flux decrease in the 3D situation for that in 1D, kDBL provides a measure of how much the sampler flux is changed in the 3D geometry compared to the common 1D solutions of the DGT equation.
In order to explore further the regulation of flux through the non-dominant interactions, we examined the flux profiles between dominant interactions, normalizing the flux through each sequence against the flux through the first interaction in the sequence.
Our results also show the stronger presence of winter anomaly during the years of higher solar flux and it has been confirmed by normalizing the difference of winter to summer foF2 values for each year.
When normalizing the predicted fluxes by the overall flux through the enzyme associated reactions, an increased relative uptake of glucose is observed as the objective value decreases.
Flux distributions were normalized by the flux of glucose to glucose-6-phosphate, and results for several central carbon metabolism reactions can be found in the supplemental information (Additional file 7: Figure S2).
In agreement, leucine normalized the autophagic flux to the level observed in cells cultured in complete medium, as shown by the absence of LC3-II accumulation (Fig. 3B) and impaired degradation of SQSTM1 (Fig. 3C).
The normalisation of the powerlaw model is not important here, since the calculation of the weights involves normalizing the model values by the total model flux.
This is tantamount to normalizing the curvature by multiplying it by the Taylor scale of turbulence.
By choosing that, we have finished normalizing the distance metric.
Since the overall rate of metabolism differed widely, as can be seen from the substrate uptake rates (Table 1), we normalized the calculated metabolic fluxes by the uptake rate to enable a direct comparison.
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