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Results are plotted as a "stress fiber induction index" which was obtained by normalizing each treatment to the starved condition.
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Relative percent viability was determined by normalizing each condition to DMSO treatment only.
Luciferase-fold induction was calculated by normalizing the results to control treatment, which was assumed as 1-fold induction.
The ligand-independent (LI) gene signature was created by normalizing the gene expression values in -R5020 treatment group in WT or KR expressing cells to the -R5020 treatment group in the PR-null expressing cells, then comparing those normalized fold change values between the KR and WT expressing cell lines.
The relative tumor volume was calculated by normalizing the tumor volume of each week to that on the treatment day.
Both patients responded positively to the treatment as measured by normalizing T lymphocyte counts in the blood as well as by an increase in ADA enzyme activity in one patient (Blaese et al, 1995).
Percentage inhibition for individual treatment groups are calculated by normalizing Area Under the Curve (AUC) for paw swelling and withdrawal threshold by fitting SCW vehicle groups to 100% and non-arthritic controls to 0%.
Amygdala function is altered in patients with bipolar disorder (BD), but may be normalized by treatment with mood stabilizers.
A role for AR in these changes was further confirmed when we observed that they could be normalized by treatment of cells with Sorbinil, an AR inhibitor.
We recently reported [Proc. Natl. Acad. Sci. USA 95 (1998 3239]] that in patients with severe depression there is a decrease in the CSF levels of 3α,5α-TH PROG, which is normalized by treatment with drugs (i.e. fluoxetine) that improve psychopathology.
CCl4-induced hepatic cirrhosis decreased hepatic glutathione (GSH) and increased lipid peroxidative products (TBARS), were normalized by treatment with SME.
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