Sentence examples for by negative selection during from inspiring English sources
Figure 5A demonstrates the extent to which the frequency of a mutation can be skewed by negative selection during the course of an infection.
This suggests that WAR1 and YRR1 do not evolve neutrally: these two genes are either subject to the accumulation of slightly deleterious mutations that are eliminated by negative selection during speciation, or alternatively they present substantial diversity that might be associated with balanced selection resulting from specific adaptation of the strain to wine fermentation conditions.
This suggests that PDR8 is subject to the accumulation of slightly deleterious mutations that are eliminated by negative selection during speciation, or alternatively that PDR8 presents substantial diversity that might be associated with balanced selection resulting from specific adaptation to different niches.
Despite the pervasive role played by negative selection affecting genes expressed during embryogenesis, we detected cases of PSG that are involved in the three embryonic stages studied and in the six species of the D. melanogaster group (supplementary table S3, Supplementary Material online).
Generally HERV-encoded genes are thought to be inactivated by negative selection, followed by degeneration due to mutational decay during evolution.
Conservation of DNA elements by negative selection, such as CNCs, suggests that these sequences have maintained a function during evolution.
Therefore, T cells were not exposed to insulin peptides during their development leaving insulin-specific T cells untouched by negative selection.
Still, infection with metacyclic forms enriched by negative selection can induce more homogenous results when evaluating the quality of immune responses during L. braziliensis or L. amazonensis human macrophage infection.
