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It was proposed that acquisition of plasmid pXO1 and pathogenicity may require a dampening of sporulation regulation by mutational selection of sporulation sensor histidine kinase defects.
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The selection-mutation-drift theory of synonymous codon usage describes an equilibrium condition where preferred and non-preferred codons occur in proportions determined by mutational biases, selection, and effective population size.
Thus, a range of duplication events followed by mutational drift and selection is at the basis of the current diversity of membrane transporters in strain BS001.
Reduced protein expression of mutein PaHNL5-L1Q-A111G was remedied by mutational anticipation of posttranslational deamidation.
In conclusion, the probability of mitonuclear coadaptation depends on standing variation, modulated by mutational rates, and intensity of purifying selection.
Mutational events and selection of the optimal variant are essential to obtain a better catalyst.
The population scale is influenced by the mutational input, selection regimes, and stochastic changes affecting the size and structure of populations, which eventually determine the evolutionary fate of mutations.
It was found that codon usage bias in Mimivirus genes is dictated both by mutational pressure and translational selection.
This pattern does not become less pronounced as more and more distant genomes are included into consideration, indicating that it is not caused by the effect of polymorphisms reflecting mutation-selection balance influenced by mutational asymmetries [ 7, 9].
The mutational diversification and clonal selection of hPSCs in culture is an inevitability of basic evolutionary principles.
The vital importance of bases A1492, A1493 and G530 in aa-tRNA selection was revealed by mutational analysis (Cochella et al, 2007).
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