Sentence examples for by mutational profiling of from inspiring English sources

As a consequence of the proposed difference in the mutational spectrum in CSC and differentiated cells of the two models, we sought to investigate this by mutational profiling of the different cancer cell populations.

Our tumor set was validated by previous mutational profiling of common cancer genes, including the IDH1 gene [21].

The inclusion of LOH mutations correctly identified an additional 2 cases of aggressive disease for a total of 8/17 cases of aggressive disease identified by mutational profiling.

26 patients categorized with a cytology diagnosis of atypical, negative or indeterminate were analyzed by mutational profiling.

Those with insufficient amounts of amplifiable DNA were categorized as "non-diagnostic" by mutational profiling.

All 7 patients with negative cytology were negative by mutational profiling.

In addition, no patients with non-aggressive disease had positive results by mutational profiling.

Patients with associated surgical or clinical follow-up outcomes were examined by cytopathology as well as mutational profiling of DNA from microdissected cytology slides and from supernatant fluid, which is normally otherwise discarded.

When added to first line cytology testing, mutational profiling of specimens that were atypical, negative, or indeterminate by cytology increased the detection of aggressive disease and the diagnostic yield of specimens regardless of cellularity.

Schniederjans, M., Koska, M. & Häussler, S. Transcriptional and mutational profiling of an aminoglycoside-resistant Pseudomonas aeruginosa small-colony variant.

Mutational profiling of invasive ductal breast cancers has yielded potential targets for directed cancer therapy, yet most studies have not included neuroendocrine carcinomas.