Sentence examples for by mutation of a from inspiring English sources

Fig. 2 Opsin originated by mutation of a "serpentine protein" [also called G-protein-coupled receptor (GPCR)].

Furthermore, there was no genetic match between the tumors and the dogs, which would be expected if the tumors arose by mutation of a dog's own cells.

There are two X-linked sideroblastic anemias (XLSAs), one caused by mutations of an erythroid-specific form of the heme biosynthetic enzyme aminolevulinic acid-synthase (ALAS2) [6], and one caused by mutation of a mitochondria-localized transport protein, ATP-binding cassette, member b7 (ABCb7) [7]—that plays a role in maturation/transport of iron-sulfur cluster containing proteins.

Constructs encoding catalytically inactive PDE4D variants were generated by mutation of a critical histidine residue in the catalytic site of PDE4D to alanine (His326 in PDE4D3).

In maize, the transition from the mitotic to meiotic cell cycle can be abolished by mutation of a single gene, ameiotic1 (Golubovskaya et al. 1993, 1997).

Disturbances in regulation of P homeostasis, e.g. by mutation of a phosphate regulator such as PHO2, can therefore interfere with the plants adaptation capacity to stress [ 103].

Instead, opsins arose by mutation of an existing receptor to render it light-sensitive.

The GDD sequence is essential for HEV replicase activity, as demonstrated by mutation of an enhanced green fluorescent protein (EGFP -containing HEGFP -containing

Essentially, this is an extension of the coding region by mutation of an existing termination codon into one specifying an amino acid, so that the ORF is extended until the next occurrence of an in-frame termination codon.

This method relies on several assumptions, namely: (1) unique genotypes originate from a zygote rather than by mutation of an existing genotype; (2) mating is random [this may be violated in clonal populations (Cook, 1983)]; and (3) genotypes at separate loci are independent.

For 3TC an additional explanation is that this drug is highly influenced by mutations of a single residue, M184, to V or I.