Sentence examples for by mutation in a from inspiring English sources

Avise describes the MMBID, The Metabolic and Molecular Bases of Inherited Disease, a reference work of 255 chapters, each of which is about a heritable disease caused by mutation in a coding sequence.

Rather, Jobling says, this characteristic could have arisen by mutation in a small founder population and then simply spread as this population migrated to other parts of the world.

RAS activation has long been associated with proliferative signals, and RAS itself is activated by mutation in a large number of human cancers.

Changes in the brain structure of NF1 patients can be global, and possibly caused by mutation in a single Nf1 allele (van Engelen et al., 2008; Karlsgodt et al., 2012).

TβR-II is inactivated by mutation in a majority of colon and gastric cancers with microsatellite instability [ 13**, 14, 15] and, to a smaller percentage, also in microsatellite stable colon cancers [ 16].

Such calculations confirmed that the Bacteroides population in the 1-month-old infant contained excesses of singletons and of total haplotypes (table 2), as is characteristic of a population expanding after a bottleneck, and supporting the hypothesis of colonization by a small inoculum followed by in situ diversification by mutation in a rapidly growing population.

For example, mutational changes can be easily restricted to the inner tepals and lip by mutations in a clade 3 gene, or to the lip by mutations in a clade 4 gene.

The condition, MCAD deficiency, is caused by mutations in a gene involved in fat metabolism.

Some of the earliest work has until now been with inherited diseases caused by mutations in a single gene.

Duchenne muscular dystrophy is caused by mutations in a gene on the X chromosome and affects around one in 3,500 boys.

Some diseases, like sickle cell anemia or cystic fibrosis, are caused by mutations in a single gene, and are relatively rare.