HRs were directly determined by multivariate analysis in some studies, whereas others provided Kaplan-Meier survival curves.
Differences were analyzed by multivariate analysis of variance MANOVA.
The significant effect of being intersected by railways disappeared, and the density of medical facilities showed borderline significance after correction for other factors in multivariate analysis, whereas being intersected by national highways and freeways and proximity to airports and higher population density remained as significant factors, all showing a positive association (Table 1).
One group was constituted of six studies (39– 44) that included BMI in multivariate analysis, whereas the other was constituted of three studies that only presented unadjusted measures of association without adjustment by BMI (45– 45).
High ALK mRNA levels were of prognostic relevance by Cox univariate regression analysis and correlated with increased risk of relapse (P=0.001) and survival (P=0.01), whereas by multivariate analysis elevated ALK mRNA expression resulted a negative prognostic marker when clinical stage was not included.
Factors associated with fatality by multivariate analysis were APACHE II score, cirrhosis, malignancy, pulmonary source, and septic shock, whereas urologic origin and adequate antimicrobial therapy before ICU admission were protective factors (Table 3).
By multivariate analysis, the primary negative determinants of CD were African American race and hyperparathyroidism; whereas, glomerular disease had a positive influence on capillary rarefaction (R = 64.2% variance; P = 0.001).
First, factors associated with outcome were determined by multivariate analysis.
By multivariate analysis, only MV was associated with prognosis.
We first compared patients and volunteers by multivariate analysis.
By multivariate analysis, shock on admission (OR 6.25 [2.71–14.40], p < 0.001) and the use of invasive mechanical ventilation (OR 5.06 [1.84–13.94], p = 0.02) were independently associated with mortality, whereas non-invasive ventilation was associated with decreased mortality (OR 0.31 [0.12–0.81], p = 0.02).
